GLOBAL MULTI-STAGE INVESTOR, WORLD-CLASS NETWORK
Approach
Sixty Degree Capital invests in companies creating meaningful change in their industries, across sectors (software, digital infrastructure, healthcare, biotech) and across stages (as early as Series A, as late as pre-IPO).
Advantage
We have a world-class network, specialized in-house expertise, and relationships with marquee investors. This differentiation enables us to support our portfolio companies and generate exceptional returns for our investors.
Our Portfolio
Arcellx is a clinical-stage biopharmaceutical company developing novel, adaptive and controllable cell therapies for the treatment of patients with cancer and autoimmune diseases. The Company’s vision is to expand access to cell therapies to millions of patients under the care of academic and community practices.
Antios Therapeutics is a biopharmaceutical company devoted to developing innovative therapies for viral diseases. With an experienced and proven leadership team, the company is focused on the development of its lead oral drug candidate for a potentially curative treatment of HBV infections.
Arctic Wolf
Arctic Wolf helps companies end cyber risk by providing cloud-native security operations technology. It provides solutions that include Managed Detection and Response, Managed Risk, and Managed Cloud Monitoring, each delivered through the industry’s original concierge security team. Its concierge security engineers act as an extension of a company’s internal team, providing tailored threat detection and response, as well as ongoing risk management to keep valuable business data safe.
Clearcover is the smarter car insurance choice, offering better coverage for less money. Clearcover’s customer-first, service-focused model powered by advanced technology delivers a convenient, reliable and affordable experience. Built for today’s driver, Clearcover takes the guesswork out of car insurance, making it easy to save money and get insured in minutes.
CinCor is a clinical stage cardiorenal therapeutics company with a novel clinical-stage candidate, CIN-107, that we believe has the potential to dramatically expand therapeutic options for patients suffering from hypertension and its associated risks. CIN-107 also has the potential to treat other diseases where aldosterone plays a significant role in their pathogenesis.
DataGrail
DataGrail is a data privacy start-up that helps businesses navigate the growing array of privacy regulations. It constitutes part of a growing roster of platforms that are capitalizing on privacy regulations, such as GDPR in Europe and CCPA in California, by making it easier for companies to manage, automate, and grow their privacy programs.
Engage Therapeutics is a biopharmaceutical company bringing innovative medicines to market. The company’s lead investigational drug is Staccato® alprazolam, a small, easy-to-use hand-held drug-device combination product that leverages an FDA-approved delivery system with FDA-approved alprazolam for the cessation of active and acute epileptic seizures.
Everly Health provides an e-commerce platform that enables customers to buy a variety of test kits online, collect their sample at home, and get informative results without visiting a lab or doctor's office. The platform offers various at-home lab tests including sexual health, thyroid, metabolism, men's health, and breast milk DHA testing, which the company is the exclusive provider of in the U.S.
Everside Health is a direct primary care provider offering convenient on-site, near-site, and virtual care for its members. Everside’s data-driven, patient-centric healthcare delivery model aligns incentives to benefit the patient, the physician, and the benefit provider, all while reducing the total cost of care.
GrubMarket is the most affordable farm-to-table food delivery service offering a variety of organic and locally-sourced food and produce.
Korro Bio was founded to turn extraordinary scientific insights into life-altering new treatments for patients. We harness the body’s natural RNA editing machinery to make precise, single-base RNA edits to modulate protein function, addressing the medical needs of patients. Our mission is to rewrite the future for patients living with debilitating disease by repairing the underlying genetic cause.
Libra Therapeutics is focused on developing novel disease-modifying therapeutics for Amyotrophic lateral sclerosis (ALS), Frontotemporal dementia (FTD) and other neurodegenerative diseases. The company’s therapeutic platform is uniquely positioned to discover and develop small molecule drugs with distinct molecular approaches
Lime, formerly LimeBike, is a transportation company based in San Francisco, USA. It runs electric scooters, electric bikes, normal pedal bikes, electric mopeds and car sharing systems in various cities around the world. The system offers dockless vehicles that users find and unlock via a mobile app that knows the location of available vehicles via GPS
Macrometa is an information technology company. Macrometa specializes in developing real-time stateful server-less applications. It delivers a global, stateful, real-time serverless database, event processing, and compute runtimes across 175 worldwide edge data centers. The company was founded in 2017 and headquartered in Palo Alto, California.
Miovision helps build tomorrow’s smart cities by transforming the way traffic is managed today. Backed by the world’s most advanced traffic AI, its innovations in traffic signal planning and operations have made it possible for cities to improve the transportation experience for drivers, cyclists, and pedestrians .
Monte Rosa Therapeutics is developing molecular glues to degrade disease-causing proteins. Its drug discovery platform combines diverse and proprietary chemical libraries of small molecule protein degraders with in-house proteomics, structural biology, machine learning-based target selection and computational chemistry capabilities to predict and obtain protein degradation profiles.
Northern Biologics was launched in June 2014 from Blueline Bioscience, a Canadian biotechnology incubator operated by venture capital firm Versant Ventures. The company is developing a portfolio of antibody-based therapeutics based on relevant targets in the tumor microenvironment.
Pipeline Therapeutics is creating a portfolio of first-in-class small molecules in neuro-regeneration: Synaptogenesis, Remyelination, and Axonal Repair.
Developer of a backend gaming engine designed to scale games fast, simply, and reliably. The company's engine leverages recreation, imagination, and community to provide login and connect services, lobby, matchmaking, game allocation, communication, and access to data services, enabling clients to focus excess on games rather than managing other processes.
Radius Agent is a mobile-first real estate CRM that enables real estate agents across brokerage firms to co-work. The company's solution is to increase sales conversions for every agent on its platform.
RefleXion is developing the first biology-guided radiotherapy system, a significant change in strategy from single tumor therapy to the ability to one day treat multiple tumors in the same treatment session in cancers that have metastasized. Currently, the RefleXion X1 machine is cleared for the delivery of stereotactic body radiotherapy (SBRT),stereotactic radiosurgery (SRS) and intensity modulated radiotherapy (IMRT). The company is also developing BgRT, which incorporates positron-emission tomography (PET) imaging data to enable tumors to continuously signal their location. The BgRT technology will synchronize these data with the linear accelerator to direct radiotherapy to tumors with subsecond latency.
Schrödinger’s industry-leading computational platform is used to accelerate drug discovery and materials design is deployed by leading pharmaceutical, biotechnology, chemical, and electronics companies worldwide.
Tact.ai is on a mission to make enterprise software more human-friendly. Tact.ai puts sellers first with human-friendly CRM solutions that are frictionless, connected, and prescriptive. Powered by our patented Edge AI platform, Fortune 500 sales organizations -- including Honeywell, Cisco, and one of the largest pharmaceutical companies in the
world -- use Tact to change sales behavior and digitally transform how sellers work with customers every day to achieve new levels of productivity and collaboration.
T-knife is a T-cell receptor (TCR) company building a pipeline of innovative therapeutics for solid tumor patients and their families. The company leverages its proprietary transgenic mouse platform in order to produce fully human TCRs, naturally selected in vivo for high affinity and specificity, and to develop TCR therapies that target tumor-specific antigens.
Nanjing TransThera Biosciences Co., Ltd. is an innovative small molecule new drug R&D company in Jiangbei New Area, focusing on the development of innovative drugs that are not satisfied with clinical needs with obvious differentiation.
Turnstone Biologics is a biopharmaceutical company developing intellectual property and a therapeutic platform based on discoveries from leading researchers in the oncolytic viral immunotherapy field.
Arctic Wolf
Arctic Wolf helps companies end cyber risk by providing cloud-native security operations technology. It provides solutions that include Managed Detection and Response, Managed Risk, and Managed Cloud Monitoring, each delivered through the industry’s original concierge security team. Its concierge security engineers act as an extension of a company’s internal team, providing tailored threat detection and response, as well as ongoing risk management to keep valuable business data safe.
Clearcover is the smarter car insurance choice, offering better coverage for less money. Clearcover’s customer-first, service-focused model powered by advanced technology delivers a convenient, reliable and affordable experience. Built for today’s driver, Clearcover takes the guesswork out of car insurance, making it easy to save money and get insured in minutes.
DataGrail
DataGrail is a data privacy start-up that helps businesses navigate the growing array of privacy regulations. It constitutes part of a growing roster of platforms that are capitalizing on privacy regulations, such as GDPR in Europe and CCPA in California, by making it easier for companies to manage, automate, and grow their privacy programs.
Everly Health provides an e-commerce platform that enables customers to buy a variety of test kits online, collect their sample at home, and get informative results without visiting a lab or doctor's office. The platform offers various at-home lab tests including sexual health, thyroid, metabolism, men's health, and breast milk DHA testing, which the company is the exclusive provider of in the U.S.
GrubMarket is the most affordable farm-to-table food delivery service offering a variety of organic and locally-sourced food and produce.
Lime, formerly LimeBike, is a transportation company based in San Francisco, USA. It runs electric scooters, electric bikes, normal pedal bikes, electric mopeds and car sharing systems in various cities around the world. The system offers dockless vehicles that users find and unlock via a mobile app that knows the location of available vehicles via GPS
Macrometa is an information technology company. Macrometa specializes in developing real-time stateful server-less applications. It delivers a global, stateful, real-time serverless database, event processing, and compute runtimes across 175 worldwide edge data centers. The company was founded in 2017 and headquartered in Palo Alto, California.
Miovision helps build tomorrow’s smart cities by transforming the way traffic is managed today. Backed by the world’s most advanced traffic AI, its innovations in traffic signal planning and operations have made it possible for cities to improve the transportation experience for drivers, cyclists, and pedestrians .
Developer of a backend gaming engine designed to scale games fast, simply, and reliably. The company's engine leverages recreation, imagination, and community to provide login and connect services, lobby, matchmaking, game allocation, communication, and access to data services, enabling clients to focus excess on games rather than managing other processes.
Radius Agent is a mobile-first real estate CRM that enables real estate agents across brokerage firms to co-work. The company's solution is to increase sales conversions for every agent on its platform.
Tact.ai is on a mission to make enterprise software more human-friendly. Tact.ai puts sellers first with human-friendly CRM solutions that are frictionless, connected, and prescriptive. Powered by our patented Edge AI platform, Fortune 500 sales organizations -- including Honeywell, Cisco, and one of the largest pharmaceutical companies in the
world -- use Tact to change sales behavior and digitally transform how sellers work with customers every day to achieve new levels of productivity and collaboration.
Antios Therapeutics is a biopharmaceutical company devoted to developing innovative therapies for viral diseases. With an experienced and proven leadership team, the company is focused on the development of its lead oral drug candidate for a potentially curative treatment of HBV infections.
Everside Health is a direct primary care provider offering convenient on-site, near-site, and virtual care for its members. Everside’s data-driven, patient-centric healthcare delivery model aligns incentives to benefit the patient, the physician, and the benefit provider, all while reducing the total cost of care.
Korro Bio was founded to turn extraordinary scientific insights into life-altering new treatments for patients. We harness the body’s natural RNA editing machinery to make precise, single-base RNA edits to modulate protein function, addressing the medical needs of patients. Our mission is to rewrite the future for patients living with debilitating disease by repairing the underlying genetic cause.
Libra Therapeutics is focused on developing novel disease-modifying therapeutics for Amyotrophic lateral sclerosis (ALS), Frontotemporal dementia (FTD) and other neurodegenerative diseases. The company’s therapeutic platform is uniquely positioned to discover and develop small molecule drugs with distinct molecular approaches
Pipeline Therapeutics is creating a portfolio of first-in-class small molecules in neuro-regeneration: Synaptogenesis, Remyelination, and Axonal Repair.
RefleXion is developing the first biology-guided radiotherapy system, a significant change in strategy from single tumor therapy to the ability to one day treat multiple tumors in the same treatment session in cancers that have metastasized. Currently, the RefleXion X1 machine is cleared for the delivery of stereotactic body radiotherapy (SBRT),stereotactic radiosurgery (SRS) and intensity modulated radiotherapy (IMRT). The company is also developing BgRT, which incorporates positron-emission tomography (PET) imaging data to enable tumors to continuously signal their location. The BgRT technology will synchronize these data with the linear accelerator to direct radiotherapy to tumors with subsecond latency.
T-knife is a T-cell receptor (TCR) company building a pipeline of innovative therapeutics for solid tumor patients and their families. The company leverages its proprietary transgenic mouse platform in order to produce fully human TCRs, naturally selected in vivo for high affinity and specificity, and to develop TCR therapies that target tumor-specific antigens.
Nanjing TransThera Biosciences Co., Ltd. is an innovative small molecule new drug R&D company in Jiangbei New Area, focusing on the development of innovative drugs that are not satisfied with clinical needs with obvious differentiation.
Turnstone Biologics is a biopharmaceutical company developing intellectual property and a therapeutic platform based on discoveries from leading researchers in the oncolytic viral immunotherapy field.
Arcellx is a clinical-stage biopharmaceutical company developing novel, adaptive and controllable cell therapies for the treatment of patients with cancer and autoimmune diseases. The Company’s vision is to expand access to cell therapies to millions of patients under the care of academic and community practices.
CinCor is a clinical stage cardiorenal therapeutics company with a novel clinical-stage candidate, CIN-107, that we believe has the potential to dramatically expand therapeutic options for patients suffering from hypertension and its associated risks. CIN-107 also has the potential to treat other diseases where aldosterone plays a significant role in their pathogenesis.
Engage Therapeutics is a biopharmaceutical company bringing innovative medicines to market. The company’s lead investigational drug is Staccato® alprazolam, a small, easy-to-use hand-held drug-device combination product that leverages an FDA-approved delivery system with FDA-approved alprazolam for the cessation of active and acute epileptic seizures.
Monte Rosa Therapeutics is developing molecular glues to degrade disease-causing proteins. Its drug discovery platform combines diverse and proprietary chemical libraries of small molecule protein degraders with in-house proteomics, structural biology, machine learning-based target selection and computational chemistry capabilities to predict and obtain protein degradation profiles.
Northern Biologics was launched in June 2014 from Blueline Bioscience, a Canadian biotechnology incubator operated by venture capital firm Versant Ventures. The company is developing a portfolio of antibody-based therapeutics based on relevant targets in the tumor microenvironment.
Schrödinger’s industry-leading computational platform is used to accelerate drug discovery and materials design is deployed by leading pharmaceutical, biotechnology, chemical, and electronics companies worldwide.